Integrated Drug Discovery

Integrated Solutions in Drug Discovery - From Concept to Candidate

Our Integrated Drug Discovery model offers a seamless and comprehensive pathway from target validation through to pre-clinical candidate selection. By integrating expert knowledge across various therapeutic areas, we offer innovative solutions that accelerates your drug discovery programs.

From concept to clinic, we pioneer the journey of drug discovery with our state-of-the-art facilities and multidisciplinary scientific functions.

medicinal chemistry

Biology

DMPK

toxicology

A Full-Spectrum Drug Discovery Partner

Comprehensive Drug Discovery Solution

Seamlessly combines expertise from target validation through to pre-clinical candidate selection.

Specialized Services Under One Roof

Offers a range of specialized services including medicinal chemistry, discovery biology, DMPK, and toxicology

Innovation and Efficiency

Focuses on innovation and efficiency to deliver clinically viable solutions across multiple therapeutic areas.

State-of-the-Art Facilities

Our core strength lies in utilizing state-of-the-art facilities and multidisciplinary scientific expertise to advance drug discovery.

Tailored Services

Dedicated to customizing services to meet each client's unique needs, ensuring an efficient drug discovery process.

Pioneering Drug Discovery

Our expert team passionately leads the drug discovery journey from concept to clinic.

Our multidisciplinary experts drive daily progress and regularly report to the Leadership and Steering Committee. Under the facilitation of the Project Manager (PM), cross-functional communication fosters seamless collaboration at all stages. Regular reviews and decision points strengthen our governance model, enhancing evaluation, transparency, and accountability. We prioritize continuous improvement, using insights from past projects to refine future strategies.

Our Collaborative Approach

Laxai’s integrated drug discovery (IDD) process is powered by a strategic model aimed at optimizing resources and fostering transparent decision-making. Central to this model is the Joint Steering Committee (JSC), comprising senior executives and stakeholders from various departments, guiding project direction.

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Key verticals under the Joint Steering Committee

Chemistry

Biology

DMPK project leads

Project Management (PM)

Supply Chain Management (SCM)

Compound Management System (CMS)

This adaptable framework promotes improved collaboration and decision-making, accelerating the development of innovative therapies at Laxai.

Our comprehensive range of drug discovery and
development services will support you at every stage

Precision Target Discovery

We use advanced techniques to identify and validate biological targets essential for understanding disease mechanisms. Our strategy prioritizes targets with the highest potential impact.

Hit Identification and Refinement

Using cutting-edge techniques, we identify and refine small molecule compounds that effectively interact with target proteins. This ensures a strong starting point for drug discovery

Lead Optimization Excellence

Our iterative process of lead optimization involves rigorous testing and refinement to enhance safety, efficacy, and pharmacokinetics. We prioritize building a solid structure-activity relationship (SAR) to guide further development.

Thorough Pre-Clinical Evaluation

Prior to clinical trials, we conduct comprehensive studies to assess pharmacokinetics, safety, and formulation. This meticulous preparation sets the stage for successful clinical development.

Expert Regulatory Guidance

Navigating the regulatory landscape is complex, but we provide expert support every step of the way. From IND submissions to agency interactions, we ensure compliance and efficiency.

Standout features of
Integrated Drug Discovery Service

Enhance decision-making efficiency through meticulous SAR analysis.
Superior drug candidates boast enhanced efficacy and safety.
Lower project attrition rates and boost drug discovery and development success with superior candidates that offer enhanced efficacy and safety
Harness cutting-edge technologies dedicated to drug discovery.
Foster innovation through cross-disciplinary collaboration.

Target identification and validation

We identify and validate biological targets relevant to a specific disease or pathology of interest. This may involve using computational methods or experimental assays to screen large databases of genetic, biochemical, or pharmacological data.

Hit identification and optimization

We identify and optimize small molecule compounds or initial hits interacting with the target protein. This combines virtual, high-throughput screening (biochemical/ enzymatic and cell-based) and medicinal chemistry approaches.

Regulatory support

We help navigate the regulatory landscape and ensure compliance with drug development and approval requirements such as regulatory submissions and interacting with regulatory agencies.

Pre-clinical and clinical development

We provide support for pre-clinical and clinical development of the drug candidate, including pharmacokinetic and pharmacodynamic studies, formulation development, toxicology testing, and supply of clinical trial material. Our team can also collaborate and coordinate with clinical research organizations (CROs) to conduct clinical trials.

Lead optimization

We optimize the most promising lead candidates through iterative chemical synthesis, biological testing, and computational modeling cycles to establish additive SAR (structure-activity relationship). The lead optimization process improves drug-like properties (safety, efficacy, and pharmacokinetics) following the Design Make Test Analyze (DMAT) approach.

A small molecule

CRDMO

Our Services

A small molecule

CRDMO

Our Services

A small molecule

CRDMO

Our Services

A small molecule

CRDMO

Our Services